全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Karsten Schmidt , Jochen Frederick Hernekamp , Miriam Doerr ...
来源:[J].BMC Anesthesiology(IF 1.188), 2015, Vol.15 (1)Springer
摘要:... Cytidine-5-diphosphocholine (CDP-choline) is an extensively studied cholinergic drug due to its brain protective characteristics in cerebrovascular diseases. This study evaluated the effect of CDP-choline on microvascular permeability and leukocyte adhesion during endotoxemia...
作者:Yingmiao Liu , Junzhi Wang , Chongmao Xu ...
来源:[J].Applied Microbiology and Biotechnology(IF 3.689), 2017, Vol.101 (4), pp.1409-1417Springer
摘要:Abstract(#br)Cytidine diphosphate choline (CDP-choline) has been applied for treating acute craniocerebral injury and allowing recovery of consciousness after brain surgery. In this study, an acetate kinase (ACK)/acetyl phosphate system was used to supply ATP and combined with E...
作者:Bora B. Topuz , Burcin Altinbas , Tuncay Ilhan ...
来源:[J].Brain Research(IF 2.879), 2014, Vol.1563, pp.61-71Elsevier
摘要:Abstract(#br)The present study was designed to determine the involvement of central prostaglandin synthesis on the pressor and bradycardic effect of cytidine 5′-diphosphocholine (CDP-choline). Intracerebroventricular (i.c.v.) administration of CDP-choline was made and blood ...
作者:Elif Basaran Gundogdu , Ahmet Bekar , Mesut Turkyilmaz ...
来源:[J].Journal of Surgical Research(IF 2.018), 2016, Vol.200 (2), pp.655-663Elsevier
摘要:Abstract(#br)Background(#br)CDP-choline (cytidine-5'-diphosphocholine) improves functional recovery, promotes nerve regeneration, and decreases perineural scarring in rat peripheral nerve injury. The aim of the present study was to investigate the mechanism of action of CDP-choline...
作者:Sinem Kiyici , Nesrin Filiz Basaran , Sinan Cavun ...
来源:[J].European Journal of Pharmacology(IF 2.592), 2015, Vol.764, pp.264-270Elsevier
摘要:Abstract(#br)In this study we aimed to test central administration of CDP-choline on serum ghrelin, leptin, glucose and corticosterone levels in rats.(#br)Intracerebroventricular (i.c.v.) 0.5, 1.0 and 2.0 µmol CDP-choline and saline were administered to male Wistar-Albino rat...
作者:Gulsah Uslu , Vahide Savci , Levent R. Buyukuysal ...
来源:[J].Neuroscience Letters(IF 2.026), 2014, Vol.569, pp.153-157Elsevier
摘要:... We aimed to test the effects of CDP-choline on sensorimotor gating functioning, which is an important function for the integration of sensory and cognitive information processing and the execution of appropriate motor responses. In this study, prepulse inhibition (PPI) of ...
作者:Bora B. Topuz , Burcin Altinbas , Mustafa S. Yilmaz ...
来源:[J].Respiratory Physiology & Neurobiology(IF 2.051), 2014, Vol.195, pp.50-58Elsevier
摘要:Abstract(#br)CDP-choline is an endogenous metabolite in phosphatidylcholine biosynthesis. Exogenous administration of CDP-choline has been shown to affect brain metabolism and to exhibit cardiovascular, neuroendocrine neuroprotective actions. On the other hand, little is known r...
作者:Aysen Cakir , Busra Ocalan , Cansu Koc ...
来源:[J].Physiology & Behavior(IF 3.16), 2020, Vol.213Elsevier
摘要:Abstract(#br)Cytidine 5-diphosphocholine (CDP-choline) administration has been shown to improve learning and memory deficits in different models of brain disorders. In this study, effects of CDP-choline on the well known negative effects of Rapid Eye Movements (REM) sleep depr...
作者:Luz Hernández-Esquivel , Natalia Pavón , Mabel Buelna-Chontal ...
来源:[J].Life Sciences(IF 2.555), 2014, Vol.96 (1-2), pp.53-58Elsevier
摘要:... The aim of this work was to explore the possibility that CDP-choline may circumvent heart damage and mitochondrial permeability transition.(#br)Main methods(#br)Rats were injected i.p. with CDP-choline at 20 mg/kg body weight. Heart electric behavior was followed during a clo...
作者:Su Myat Phyu , Chih-Chung Tseng , Tim Andrew Davies Smith
来源:[J].Magnetic Resonance Materials in Physics, Biology and Medicine(IF 1.863), 2019, Vol.32 (2), pp.227-235Springer
摘要:...(#br) Results(#br)SB216763 treatment decreased choline incorporation into lipids and caused an accumulation of CDP-choline which was accompanied by decreased conversion of glucose into lipid components.(#br) Conclusion(#br)SB216763 profoundly inhibits phospholipid synthesis in...

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