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作者:Anahita Rohani Shirvan , Azadeh Bashari , Nahid Hemmatinejad
来源:[J].European Polymer Journal(IF 2.562), 2019, Vol.119, pp.541-550
摘要:Abstract(#br)Buccal mucosa is considered as a convenient and easily accessible site for the drug administration for both local and systemic delivery. Mucoadhesion is a process involving chemical interactions between mucin and polymers. The use of mucoadhesive polymers in buccal d...
作者:S. Burgalassi , L. Panichi , M.F. Saettone ...
来源:[J].International Journal of Pharmaceutics(IF 3.458), 1996, Vol.133 (1), pp.1-7
摘要:Abstract(#br)Mucoadhesive patches releasing topical drugs in the oral cavity at a slow, predetermined rate may present distinct advantages over traditional dosage forms such as mouthwashes, oral gels and lozenges. The present study was concerned with the preparation and evaluatio...
作者:Vishnu Patel , Bhupendra Prajapati , Madhabhai Patel
来源:[J].Acta Pharmaceutica(IF 1.162), 2007, Vol.57 (1), pp.61-72
摘要:Design and characterization of chitosan-containing mucoadhesive buccal patches of propranolol hydrochloride Mucoadhesive buccal patches containing propranolol hydrochloride were prepared using the solvent casting method. Chitosan was used as bioadhesive polymer and different...
作者:Li , Koch , Raul ...
来源:[J].Drug Development and Industrial Pharmacy(IF 1.539), 1997, Vol.23 (3), pp.239-246
摘要:Abstract(#br) Mucoadhesive buccal patches were evaluated in vitro and in vivo using rats for release of thyrotropin-releasing homne (TRH). TRH (10% w/w) was incorporated into mucoadhesive buccal patches that were custom coformulated with silicone and organic polymers (Dow Comi...
作者:Li , Bhatt , Johnston
来源:[J].Pharmaceutical Development and Technology(IF 1.333), 1997, Vol.2 (3), pp.265-274
摘要:ABSTRACT(#br)A biocompatible, mucoadhesive buccal patch was evaluated in rabbits for transmucosal delivery of peptides. Oxytocin (OT) was incorporated into custom coformulations of Carbopol 974P and silicone polymer and the resulting plasma OT concentration versus time profi...
作者:M.A. Hassan , N.S. Barakat , M. El-Badry ...
来源:[J].Journal of Drug Delivery Science and Technology(IF 1.088), 2011, Vol.21 (5), pp.423-431
摘要:The aim of the study was to design and evaluate mucoadhesive buccal patches of naproxen for local treatment of pain and inflammations of the oral cavity. Buccal patches were fabricated by solvent casting technique using hydroxypropylmethylcellulose E4M, Eudragit RLPO, ethyl cel...
作者:Rewathi R. Shiledar , Amol A. Tagalpallewar , Chandrakant R. Kokare
来源:[J].Carbohydrate Polymers(IF 3.479), 2014, Vol.101, pp.1234-1242
摘要:Abstract(#br)A novel bilayered mucoadhesive buccal patch of zolmitriptan was prepared using xanthan gum (XG) as mucoadhesive polymer. Hydroxypropyl methylcellulose E-15 was used as film-former and polyvinyl alcohol (PVA) was incorporated, to increase the tensile strength of the patches...
作者:ChoyFun Wong , KahHay Yuen , KokKhiang Peh
来源:[J].International Journal of Pharmaceutics(IF 3.458), 1999, Vol.178 (1), pp.11-22
摘要:Abstract(#br)Controlled release buccal patches were fabricated using Eudragit NE40D and studied. Various bioadhesive polymers, namely hydroxypropylmethyl cellulose, sodium carboxymethyl cellulose and Carbopol of different grades, were incorporated into the patches, to modify thei...
作者:Amanpreet Kaur , Gurpreet Kaur
来源:[J].Saudi Pharmaceutical Journal(IF 0.954), 2011, Vol.20 (1), pp.21-27
摘要:Abstract(#br)The study was designed to develop bioadhesive patches of carvedilol hydrochloride using chitosan (CH) and pectin (PE) interpolymer complexes and to systematically evaluate their in vitro and in vivo performances. Mucoadhesive buccal patches of carvedilol were prepa...
作者:Parthasarathy Govindasamy , Bhaskar Reddy Kesavan , Jayaveera Korlakunta Narasimha
来源:[J].Asian Pacific Journal of Tropical Biomedicine, 2013, Vol.3 (12), pp.995-1002
摘要:Abstract(#br)Objective(#br)To achieve transbuccal release of carbamazepine by loading in unidirectional release mucoadhesive buccal patches.(#br)Methods(#br)Buccal patches of carbamazepine with unidirectional drug release were prepared using hydroxypropyl methyl cellulose, po...

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