全部文献期刊会议图书|学者科研项目
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作者:Angela Marina Montalbano , Giusy Daniela Albano , Giulia Anzalone ...
来源:[J].Chemosphere(IF 3.137), 2020, Vol.245
摘要:...01–1 μM) of PBDE-47, PBDE-99 and PBDE-209 on the mechanism of oxidative stress, dysregulation of cell proliferation, apoptosis, and DNA damage and repair (in term of H2AX phosphorylation ser139) in an in-vitro/ex-vivo model of bronchial epithelial cells. PBDEs (−47, −...
作者:Jhony Robison de Oliveira , Paulo Roberto da Silva , Alexandre de Paula Rogério
来源:[J].European Journal of Pharmacology(IF 2.592), 2017, Vol.805, pp.46-50
摘要:Abstract(#br)Bronchial epithelial cells are essential to airways homeostasis; however, they are also involved in exacerbation of airway inflammatory responses of patients with conditions such as asthma. Dermatophagoides pteronyssinus (Dp), the most important allergen, and lipopo...
作者:C. Di Sano , C. D'Anna , M. Ferraro ...
来源:[J].Toxicology Letters(IF 3.145), 2020, Vol.326, pp.61-69
摘要:Abstract(#br)Notch-1 intervenes in the reparative processes of mucosa by controlling cell proliferation, differentiation and stem cell maintenance. Cigarette smoke alters airway epithelial homeostasis.(#br)The present study explored whether: Smokers showed altered Notch-1 express...
作者:Daniely Cornélio Favarin , Aline Beatriz Mahler Pereira , Ivo M.B. Francischetti ...
来源:[J].Immunobiology(IF 2.814), 2020
摘要:...1-100 nM) in an in vitro model consisting in the activation of human bronchial epithelial cells (BEAS-2B) by IL-4 (50 ng/mL) or lipopolysaccharide (LPS; 10 ng/mL). Agaphelin is non-cytotoxic for BEAS-2B cells. Notably, agaphelin markedly reduces CCL2 and IL-8 production induce...
作者:Jorid B. Sørli , Marit Låg , Leni Ekeren ...
来源:[J].Toxicology in Vitro(IF 2.65), 2020, Vol.62
摘要:... i) a lung surfactant (LS) function assay to assess the acute inhalation toxicity potential, and ii) a cell model with human bronchial epithelial cells to study pro-inflammatory potential and modulation of inflammatory responses. We tested salts of four PFASs: perfluorobutane...
作者:Yanjun Wu , Yanping Li , Baoya Wang ...
来源:[J].Life Sciences(IF 2.555), 2018
摘要:Abstract(#br)Aims(#br)The aims of this study were to evaluate the effects of p62/SQSTM1 expression levels on lipopolysaccharide (LPS)-induced mucus secretion in BEAS-2B bronchial epithelial cells by measuring expression levels of the MUC5AC gene and the Mucin-5AC (MUC5AC) pr...
作者:Satoshi Matsukura , Yuki Osakabe , Ayaka Sekiguchi ...
来源:[J].Allergology International, 2016, Vol.65, pp.S17-S23
摘要:... In this study, we used bronchial epithelial cells to investigate in vitro the role of the microRNA miR-155 in the expression of chemokines associated with airway inflammation. miR-155 has previously been reported to regulate allergic inflammation.(#br)Methods(#br)BEAS-2B bronchial epithelial cells...
作者:Ming-Ju Tsai , Wei-An Chang , Shu-Fang Jian ...
来源:[J].Pathology - Research and Practice(IF 1.213), 2018
摘要:... Apoptosis of pulmonary structural cells contributes to pulmonary destruction and dysfunction. This study aimed to explore the possible mechanisms underlying decreased cell proliferation and increased apoptosis of bronchial epithelial cells of COPD.(#br)Materials and methods(#...
作者:Takahito Oyanagi , Takumi Takizawa , Akira Aizawa ...
来源:[J].Allergology International, 2017, Vol.66 (1), pp.75-82
摘要:... Little is known about the role of interferon (IFN)-γ in MUC5AC expression in human bronchial epithelial cells.(#br)Methods(#br)Human pulmonary mucoepidermoid carcinoma cell line (NCI-H292) and normal human bronchial epithelial (NHBE) cells were used to assess the effects of...
作者:E. Pace , M. Ferraro , S. Di Vincenzo ...
来源:[J].Toxicology Letters(IF 3.145), 2016, Vol.258, pp.216-226
摘要:... The present study assessed the effects of ceftaroline on TLR2 and TLR4 and on pro-inflammatory responses in airway epithelial cells (16HBE cell line and primary bronchial epithelial cells) with or without cigarette smoke extracts (CSE 10%).(#br)TLR2, TLR4, LPS binding and hum...

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