全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Eli Marie Grindedal , Cecilie Heramb , Inga Karsrud ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:... The aim of this report was to address these issues by evaluating the results of BRCA testing of BC patients in South-Eastern Norway.
作者:Melissa M. Straub , Mirna B. Podoll , Stephanie N. David ...
来源:[J].Annals of Diagnostic Pathology(IF 0.975), 2018Elsevier
摘要:Abstract(#br)Risk-reducing salpingo-oophorectomy (RRSO) is a procedure to reduce the risk of adnexal cancer in BRCA mutation carriers and for hormonal manipulation in women with breast cancer (BC). The goal of the study is to report the frequency of subsequent BC and high-grade ...
作者:Diana M. Eccles , Judith Balmaña , Joe Clune ...
来源:[J].Advances in Therapy(IF 2.125), 2016, Vol.33 (2), pp.129-150Springer
摘要:Abstract(#br) Introduction(#br)One of the most significant risk factors for the development of ovarian cancer (OC) is a genetic mutation in BRCA1 (breast cancer gene 1) or BRCA2 . Here we describe the impact of previous and current guidance on BRCA testing practices and provide...
作者:Annemiek Visser , Judith B Prins , Nicoline Hoogerbrugge ...
来源:[J].BMC Women's Health(IF 1.505), 2011, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br) BRCA mutation carriers have a 40-80% life-time risk of developing breast cancer. They may opt for yearly breast cancer surveillance or for prophylactic mastectomy. Both options show increased survival rates. It is a complex choice to be made between ...
作者:Hoogerbrugge Nicoline , Prins Judith B , Visser Annemiek ...
来源:[J].BMC Women's Health(IF 1.505), 2011, Vol.11 (1)DOAJ
摘要:Abstract Background BRCA mutation carriers have a 40-80% life-time risk of developing breast cancer. They may opt for yearly breast cancer surveillance or for prophylactic mastectomy. Both options show increased survival rates. It is a complex choice to be made between these two ...
作者:Priyanka Sharma , Jennifer R. Klemp , Bruce F. Kimler ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2014, Vol.145 (3), pp.707-714Springer
摘要:... All patients underwent BRCA1/2 testing. Significant family history (SFH) was defined >1 relative with breast cancer at age ≤50 or ≥1 relative with ovarian cancer. Mutation prevalence in the entire cohort and subgroups was calculated. 207 TNBC patients were enrolled betwe...
作者:J. Kim , L. Johnson , C. Skrzynia ...
来源:[J].Cancer Causes & Control(IF 3.2), 2015, Vol.26 (8), pp.1087-1092Springer
摘要:Abstract(#br) Purpose(#br)Major clinical characteristics of BRCA1/2 -related cancers include association with estrogen and metabolic consequences. We aimed to evaluate serum estradiol (E2) and insulin-like growth factor 1 (IGF-1) levels as a marker of insulin resistance in BRCA...
作者:Elizabeth Gilbert , Emily C. Zabor , Michelle Stempel ...
来源:[J].Annals of Surgical Oncology(IF 4.12), 2017, Vol.24 (10), pp.3048-3054Springer
摘要:Women with a BRCA mutation have significantly elevated breast cancer risk, which can be reduced by >90% with bilateral prophylactic mastectomy (BPM). We sought to compare a cohort of BRCA mutation carriers choosing BPM versus breast surveillance to better elucidate factors that m...
作者:Julia Krammer , Katja Pinker-Domenig , Mark E. Robson ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.163 (3), pp.565-571Springer
摘要:To describe imaging findings, detection rates, and tumor characteristics of breast cancers in a large series of patients with BRCA1 and BRCA2 mutations to potentially streamline screening strategies.
作者:Sarah Schott , Lisa Vetter , Monika Keller ...
来源:[J].Archives of Gynecology and Obstetrics(IF 1.33), 2017, Vol.295 (6), pp.1451-1458Springer
摘要:Some women of families at high risk of breast cancer (BC) choose prophylactic mastectomy (PM) in spite of ambiguous evidence for survival benefits. The aim of this study was to investigate counselees’ characteristics, decisions on PM, and frequencies of different procedures ...

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