全部文献期刊会议图书|学者科研项目
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作者:Rui Jia , Carlos M. Guardia , Jing Pu ...
来源:[J].Autophagy(IF 12.042), 2017, Vol.13 (10), pp.1648-1663
摘要:... Further experiments show that BORC KO impairs both the encounter and fusion of autophagosomes with lysosomes. Reduced encounters result from an inability of lysosomes to move toward the peripheral cytoplasm, where many autophagosomes are formed. However, BORC KO also reduces ...
作者:Yue Zhang , Ning Pan , Yemeng Sheng ...
来源:[J].Immunology Letters(IF 2.337), 2019, Vol.216, pp.36-42
摘要:... Our previous work has indicated that tumor cell-released autophagosomes (TRAPs) are sufficient to suppress anti-tumor immune response in mouse by inducing IL-10-producing B cells through high-mobility group B1 (HMGB1). Here, we hypothesized that hypoxia or starvation might ex...
作者:Heng Wang , Yuqi Zhou , Qicheng Zhu ...
来源:[J].Journal of Dairy Science(IF 2.566), 2019, Vol.102 (9), pp.8264-8272
摘要:... After infection, the formation of the autophagosomes increased but the autophagosomes and lysosomes could not fuse normally to form autolysosomes. When the formation of the autophagosomes was enhanced or the degradation of the autolysosomes was inhibited, the number of Staph....
作者:Ke Ming , Wenjuan Yuan , Yun Chen ...
来源:[J].Carbohydrate Polymers(IF 3.479), 2018, Vol.208
摘要:... However, CIPS treatment significantly downregulated the expressions of LC3-II and PI3KC3 induced by DHAV and rapamycin, and consequently inhibited autophagosomes formation. As a result, DHAV replication was inhibited.
作者:Monica Fengsrud , Egil S. Erichsen , Trond O. Berg ...
来源:[J].European Journal of Cell Biology(IF 3.213), 2000, Vol.79 (12), pp.871-882
摘要:Summary(#br)The delimiting membranes of isolated autophagosomes from rat liver had extremely few transmembrane proteins, as indicated by the paucity of intramembrane particles in freeze-fracture images (about 20 particles/μm 2 , whereas isolated lysosomes had about 2000 particl...
作者:Elizabeth M.H. Duke , Minoo Razi , Anne Weston ...
来源:[J].Ultramicroscopy(IF 2.47), 2014, Vol.143, pp.77-87
摘要:... In this study, we used cryo-SXT to image endosomes and autophagosomes, organelles that are particularly susceptible to chemical fixation artefacts during sample preparation for electron microscopy. We used two approaches to identify these compartments. For early and recycli...
作者:Hui Zou , Tao Wang , Junzhao Yuan ...
来源:[J].Toxicology Letters(IF 3.145), 2020, Vol.321, pp.32-43
摘要:... However, the fusion of autophagosomes with lysosomes was inhibited by Cd both in vivo and in vitro . Next, the expression of Rab7, a key protein that regulates autophagosome–lysosome fusion, was examined. Cd was found to inhibit Rab7 expression both in vivo and in vitro ....
作者:Andrea Diana
来源:[J].Translational Neuroscience(IF 0.482), 2012, Vol.3 (4), pp.384-387
摘要:... In this review we focus our attention on major alterations affecting two organelles: autophagosomes and multivesicular bodies, both of which are located at the intersection point of their respective pathways.
作者:Masaaki Uematsu , Taki Nishimura , Yuriko Sakamaki ...
来源:[J].Autophagy(IF 12.042), 2017, Vol.13 (8), pp.1452-1464
摘要:... Purification of autophagosomes before fusion with lysosomes is important for both mechanistic and physiological studies of the autophagosome. Here, we report a simple method to accumulate undigested autophagosomes. Overexpression of the autophagosomal Qa-SNARE STX17 (synta...
作者:Xie Rui , Nguyen Susan , McKeehan Wallace ...
来源:[J].BMC Cell Biology(IF 2.808), 2010, Vol.11 (1), pp.89
摘要:Abstract Background Autophagy is a dynamic process during which isolation membranes package substrates to form autophagosomes that are fused with lysosomes to form autolysosomes for degradation. Although it is agreed that the LC3II-associated mature autophagosomes move along micr...

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