全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Meiling Liu , Sanghoon Moon , Longfei Wang ...
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)Springer
摘要:Copy number variation (CNV) is known to play an important role in the genetics of complex diseases and several methods have been proposed to detect association of CNV with phenotypes of interest. Statistical methods for CNV association analysis can be categorized into two differe...
作者:Lucas L. Verardo , Marja-Liisa Sevón-Aimonen , Timo Serenius ...
来源:[J].BMC Genetics(IF 2.808), 2017, Vol.18 (1)Springer
摘要:... after a quality check, 42,385 SNPs remained for association analysis. All the boars were purebred Finnish Yorkshire. To account for relatedness of the animals, a pedigree-based relationship matrix was used in a mixed linear model to test the effect of SNPs on pH measured from...
作者:Arnd Gross , Anke Tönjes , Markus Scholz
来源:[J].BMC Genetics(IF 2.808), 2017, Vol.18 (1)Springer
摘要:When testing for SNP (single nucleotide polymorphism) associations in related individuals, observations are not independent. Simple linear regression assuming independent normally distributed residuals results in an increased type I error and the power of the test is also affecte...
作者:Yujia Sun , Kunpeng Liu , Yongzhen Huang ...
来源:[J].Science China Life Sciences(IF 2.024), 2018, Vol.61 (7), pp.826-835Springer
摘要:... Here, we performed differential expression analysis of FOXO1 and its association analysis with growth traits in QC cattle. First, we measured the expression of the FOXO1 gene in nine tissues during three developmental stages. The results showed that FOXO1 was abundantly expre...
作者:Suyeon Park , Sungyoung Lee , Young Lee ...
来源:[J].BMC Medical Genetics(IF 2.536), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)In family-based association analysis, each family is typically ascertained from a single proband, which renders the effects of ascertainment bias heterogeneous among family members. This is contrary to case–control studies, and may introduce samp...
作者:Xingshuo An , Jingtao Su , Xing Lü ...
来源:[J].EURASIP Journal on Wireless Communications and Networking(IF 0.54), 2018, Vol.2018 (1), pp.1-9Springer
摘要:... This model can effectively describe the association between fog nodes which are suffering from the threat of DDoS. Through simulation, we verify that the resource utilization rate of the system can be effectively promoted through the DDoS association analysis.
作者:Dokyoon Kim , Anna O. Basile , Lisa Bang ...
来源:[J].BMC Medical Informatics and Decision Making(IF 1.603), 2017, Vol.17 (1)Springer
摘要:... In this study we developed a novel biological knowledge-based binning approach for rare-variant association analysis and then applied the approach to structural neuroimaging endophenotypes related to late-onset Alzheimer’s disease (LOAD).
作者:Kwangsik Nho , Sungeun Kim , Emrin Horgusluoglu ...
来源:[J].BMC Medical Genomics(IF 3.466), 2017, Vol.10 (1)Springer
摘要:... The region surrounding APOE on chromosome 19 has also shown consistent association with LOAD. However, no common variants in the region remain significant after adjusting for APOE genotype. We report a rare variant association analysis of genes in the vicinity of APOE with c...
作者:Yannick Girardeau , Anne-Sophie Jannot , Gilles Chatellier ...
来源:[J].BMC Medical Informatics and Decision Making(IF 1.603), 2017, Vol.17 (1)Springer
摘要:... Our objective was to confirm the impact of borderline dysnatremia for patients admitted to hospital on in-hospital mortality using real life care data from our electronic health record (EHR) and a phenome-wide association analysis (PheWAS).
作者:Katharina Correa , Jean P. Lhorente , María E. López ...
来源:[J].BMC Genomics(IF 4.397), 2015, Vol.16 (1)Springer
摘要:... A Genome Wide Association Analysis was performed on data from the challenged fish. Linear regression and logistic regression models were tested.(#br) Results(#br)Genome Wide Association Analysis indicated that resistance to P. salmonis is a moderately polygenic trait. There...

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