全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Manjusha M. Kulkarni , Annette N. Ratcliff , Menakshi Bhat ...
来源:[J].Retrovirology(IF 5.657), 2017, Vol.14 (1)Springer
摘要:Like all viruses, HIV-1 relies on host systems to replicate. The human purinome consists of approximately two thousand proteins that bind and use purines such as ATP, NADH, and NADPH. By virtue of their purine binding pockets, purinome proteins are highly druggable, and many exis...
作者:A Imaz , J Niubó , AD Kashuba ...
来源:[J].HIV Medicine(IF 3.155), 2017, Vol.18 (3), pp.225-230Wiley
摘要:Objectives(#br)The aim of the study was to quantify elvitegravir ( EVG ) concentrations in the semen of HIV ‐1‐infected men receiving antiretroviral therapy ( ART ) consisting of an elvitegravir/cobicistat/emtricitabine/tenofovir ( EVG / COBI / FTC / TDF ) single‐tablet...
作者:Theodore J Cory , Lee C Winchester , Brian L Robbins ...
来源:[J].Bioanalysis(IF 3.253), 2015, Vol.7 (12), pp.1447-1455Future Science Group
摘要:Background: Determination of cell-associated antiretroviral drug concentrations is necessary for research into reservoirs of HIV. Variation exists in cell-associated drug concentrations among research groups. One cause for this may be washing cells during processing. We explored ...
作者:Anthony T Podany , Curtis Sheldon , Daryl Grafelman ...
来源:[J].Bioanalysis(IF 3.253), 2015, Vol.7 (24), pp.3085-3095Future Science Group
摘要:Background: A novel method was developed and validated to measure tenofovir in human plasma. Results/Methodology: This method employed solid phase analytical derivatization and analysis by LC–MS/MS. Stable-labeled internal standard was added to plasma samples followed by sol...
作者:Craig R Rayner , Lori D Esch , Heather E Wynn ...
来源:[J].Annals of Pharmacotherapy(IF 2.567), 2001, Vol.35 (11), pp.1391-1395Sage国际出版集团
摘要:OBJECTIVE:(#br)To report a case of symptomatic hyperbilirubinemia resulting from the addition of ritonavir to an indinavir-containing antiretroviral regimen.(#br)CASE SUMMARY:(#br)A 27-year-old white woman developed symptomatic hyperbilirubinemia and anemia while receiving a...
作者:Jackson Akil , Else Laura , Higgs Christopher ...
来源:[J].HIV clinical trials, 2018, Vol.19 (1), pp.31-37PubMed
摘要:We aimed at investigating the antiviral activity and the pharmacokinetics of the dual antiretroviral (ARV) combination of rilpivirine plus darunavir/ritonavir 25/800/100 mg once-daily in naïve HIV-1-infected individuals (NHII) with different baseline viral loads.;;Pharmacok...
作者:Imaz A , Niubó J , Kashuba A D ...
来源:[J].HIV medicine, 2017, Vol.18 (3), pp.225-230PubMed
摘要:The aim of the study was to quantify elvitegravir (EVG) concentrations in the semen of HIV-1-infected men receiving antiretroviral therapy (ART) consisting of an elvitegravir/cobicistat/emtricitabine/tenofovir (EVG/COBI/FTC/TDF) single-tablet regimen.;;A phase IV, cross-sect...
作者:V. R. Mehta
来源:[J].The Indian Journal of Pediatrics(IF 0.715), 1983, Vol.50 (5), pp.547-551Springer
摘要:... A note on future trends in antiviral pharmacology has been added.
作者:方学平
来源:[D].中国人民解放军军事医学科学院  2005CNKI
摘要:呼吸道合胞病毒(RSV)是导致婴幼儿急性下呼吸道感染的最重要的病原体,同时也是致使某些免疫抑制人群和年老人群发病和死亡的重要的原因。目前,唯一允许用于化学疗法的药物是病毒唑,它被严格用于高危...
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