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作者:Romina J. Pagliero , Marcel Kaiser , Reto Brun ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2017, Vol.27 (17), pp.3945-3949
摘要:Abstract(#br)A library of 89 synthetic benzenesulfonyl derivatives of heterocycles with drug-like properties was assayed for in vitro antiparasitic activity and the results were added to our previously reported derivatives for a comprehensive SAR evaluation. Four compounds sho...
作者:Puspha Kumari , Saurav Kumar , M. Ramesh ...
来源:[J].Aquaculture(IF 2.009), 2019, Vol.511
摘要:...5 g L −1 for its antiparasitic effect against adult Argulus japonicus in goldfish, Carassius auratus under in vitro and in vivo conditions for 6 and 72 h, respectively . Under in vitro condition for 6 h, antiparasitic efficacy of neem leaf extracts prepared in different s...
作者:Huan Wang , Wei Tang , Rui Zhang ...
来源:[J].Fish and Shellfish Immunology(IF 2.964), 2018
摘要:... In the present work, the activity of immune-related enzymes (lysozyme, protease, antiprotease, cathepsin B, alkaline phosphatase and peroxidase), the antibacterial activity against two Gram-positive bacteria and five Gram-negative bacteria, the antiparasitic activity again...
作者:Yao-Wu Fu , Bin Wang , Qi-Zhong Zhang ...
来源:[J].Veterinary Parasitology(IF 2.381), 2018
摘要:... The present study aimed to investigate the efficacy and antiparasitic mechanism of active compounds isolated from Zingiber officinale against I. multifiliis . Three compounds were isolated from the Z. officinale extract and identified as 10-gingerol, 6-dehydroshogaol, and 6...
作者:M. Zuffo , A. Stucchi , J. Campos-Salinas ...
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2018
摘要:... Therefore, G4 could be considered as potential targets for a novel approach towards the development of antiparasitic drugs. Recently, we have demonstrated that G4 ligands such as carbohydrate naphthalene diimide conjugates (carb-NDIs) possess notable antiparasitic activity. H...
作者:Tsuyoshi Goto , Noritaka Hirazawa , Yoshihisa Takaishi ...
来源:[J].Aquaculture(IF 2.009), 2015, Vol.435, pp.173-177
摘要:Abstract(#br)The antiparasitic effects of 59 water- and methanol-soluble herbal extracts were screened for their potential to inhibit cilia-based motility of the protozoan, Cryptocaryon irritans , during its infective (theront) phase. Both the water- and methanol-soluble ext...
作者:Amber Hackler , Stephen L. Patrick , Elizabeth W. Kahney ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2017, Vol.27 (4), pp.755-758
摘要:Abstract(#br)A sulfonamidebenzamide series was assessed for anti-kinetoplastid parasite activity based on structural similarity to the antiparasitic drug, nifurtimox. Through structure-activity optimization, derivatives with limited mammalian cell toxicity and increased potency...
作者:Suélen Serafini , Junior Gonçalves Soares , Camila Felicetti Perosa ...
来源:[J].Environmental Toxicology and Pharmacology(IF 2.005), 2019, Vol.72
摘要:Abstract(#br)The objective of this study was to evaluate the toxicity of the antiparasitic agent eprinomectin in two subtropical soils, using ecotoxicological lethality, reproduction and avoidance behavior tests with springtails ( Folsomia candida ). Eprinomectin concentrati...
作者:A.M. Jarrad , A. Debnath , Y. Miyamoto ...
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2016, Vol.120, pp.353-362
摘要:... Using this approach, derivatisation of the nitroimidazole carboxamide scaffold provided improved antiparasitic agents. Thirty-three novel nitroimidazole carboxamides were synthesised and evaluated for activity against G. lamblia and E. histolytica . Several of the new compou...
作者:İlhami Gulçin , Parham Taslimi , Ayşenur Aygün ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2018, Vol.119, pp.741-746
摘要:... Indeed, these molecules can be elective inhibitors of GST, α-glycosidase and α-amylase enzymes as antidiabetic and antiparasitic agents.

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