全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Shih-Hurng Loh , Wei-Hwa Chen , Cheng-Hsien Chiang ...
来源:[J].Journal of Biomedical Science(IF 2.458), 2002, Vol.9 (3), pp.198-205Springer
摘要:... In addition to the housekeeping Na + -H + exchanger (NHE), the Na + -HCO 3 − symporter (NHS) has been demonstrated in animal cardiomyocytes as another and extruder. However, whether the NHE and NHS functions exist in human atrial cardiomyocytes remains unclear. We therefor...
作者:Yi-Ting Tsai , Chung-Yi Lee , Chao-Chin Chuang ...
来源:[J].The Chinese Journal of Physiology(IF 0.748), 2015, Vol.58 (4), pp.228-236Airiti
摘要:... Na^+-H^+ exchanger (NHE), a ubiquitously expressed transmembrane protein, has been found widely as a major acid extruder in many different cell types, including human monocytes. We therefore investigated the mechanism of the active pH_i recovery from intracellular acidosis (...
作者:Choi Inyeong , Romero Michael F , Khandoudi Nassirah ...
来源:[J].American journal of physiology. Cell physiology, 1999, Vol.276 (3), pp.C576-C584PubMed
摘要:... hhNBC is identical to human renal NBC (hkNBC), except for the amino terminus, where the first 85 amino acids in hhNBC replace the first 41 amino acids of hkNBC. About 50% of the amino acid residues in this unique amino terminus are charged, compared with ∼22% for the corre...
作者:Leif Hertz , Dan Song , Baoman Li ...
来源:[J].Journal of Signal Transduction, 2014, Vol.2014Hindawi
摘要:Chronic treatment with fluoxetine or other so-called serotonin-specific reuptake inhibitor antidepressants (SSRIs) or with a lithium salt “lithium”, carbamazepine, or valproic acid, the three classical antibipolar drugs, exerts a multitude of effects on astrocytes, which in ...
作者:Pappas C A , Rioult M G , Ransom B R
来源:[J].Glia(IF 5.066), 1996, Vol.16 (1), pp.7-15PubMed
摘要:... Octanol (1 mM) caused an acid shift in the pHi of 90% of rat hippocampal astrocytes which averaged -0.19 +/- 0.09 pH units in magnitude. In 58% of the cells tested, a biphasic change in pHi was seen; octanol produced an initial acidification lasting approximately 10 min that ...
作者:Qing Zhao , Yongzhe Che , Qiang Li ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2015, Vol.468 (4), pp.746-751Elsevier
摘要:Abstract(#br)The voltage-gated proton channel Hv1 is a potent acid extruder that participates in the extrusion of the intracellular acid. Here, we showed for the first time, Hv1 is highly expressed in mouse and human pancreatic islet β-cells, as well as β-cell lines. Imaging ...
作者:Dan Song , Yi Man , Baoman Li ...
来源:[J].Neurochemical Research(IF 2.125), 2013, Vol.38 (11), pp.2364-2374Springer
摘要:... This increase has at least two energy-consuming consequences: (1) a depolarization-mediated change in intracellular pH (pH i ) in astrocytes due to depolarization-mediated increased activity of the acid-extruding Na + /bicarbonate transporter NBCe1 (driven by secondary ac...
作者:Ahlam I. Salameh , Christian A. Hübner , Walter F. Boron
来源:[J].The Journal of Physiology(IF 4.38), 2017, Vol.595 (1), pp.93-124Wiley
摘要:... AE3 speeds re‐alkalization after removal of MAc in neurons and astrocytes, and speeds neuronal pHi recovery from an ammonium prepulse‐induced acid load. We propose that neuronal AE3 indirectly increases acid extrusion in (a) neurons via Cl loadi...
作者:Mario Strazzabosco , Carlo Poci , Carlo Spirlì ...
来源:[J].Hepatology(IF 12.003), 1995, Vol.22 (2), pp.588-597Elsevier
摘要:... To investigate intracellular acid/base homeostasis in hepatoma cells and the effects of putative liver growth factors on Na + H + exchange activity, we have studied intracellular pH (pHi) regulation in Hep G2 cells, a well-differentiated hepatoma cell line, both in resting...
作者:R. Busche , A. Jeromin , W. Engelhardt ...
来源:[J].Pflügers Archiv European Journal of Physiology(IF 4.866), 1993, Vol.425 (3-4), pp.219-224Springer
摘要:...2 mM 4,4′-diisothiocyanatodihydrostilbene-2, 2′-disulphonic acid. A basolateral Cl − / HCO 3 − exchanger is the most likely explanation for this observation. The Na + /H + exchange mechanism in the basolateral membrane is an acid extruder, whereas the C1 − /HCO 3...

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