全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Luca Cindolo , Clara Natoli , Cosimo De Nunzio ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:To evaluate the safety and efficacy of abiraterone acetate (AA) in the “real life” clinical practice for men with chemotherapy-naïve metastatic castration-resistant prostate.
作者:Darren M. C. Poon , Kuen Chan , S. H. Lee ...
来源:[J].BMC Urology(IF 1.694), 2016, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)There is much interest in confirming whether the efficacy of abiraterone acetate (AA) demonstrated within the trial setting is reproducible in routine clinical practice. We report the clinical outcome of metastatic castration-resistant prostate cance...
作者:Nadine Houédé , Philippe Beuzeboc , Sophie Gourgou ...
来源:[J].BMC Cancer(IF 3.333), 2015, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)COU-AA-301 trial has proved that abiraterone acetate (AA), a selective inhibitor of androgen biosynthesis, improved overall survival (OS) of patients with metastatic castration resistant prostate cancer (mCRPC) after a first line of docetaxel. Bas...
作者:Carsten-Henning Ohlmann , Michelle Jäschke , Peter Jaehnig ...
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
摘要:... Especially upon treatment with the life-prolonging cytochrome P450 17-alpha-hydroxylase (Cyp17)-inhibitor, abiraterone, which has the ability to further suppress testosterone serum levels over LHRH therapy alone, continuation of LHRH therapy seems to be negligible. However...
作者:Phillip Mikah , Laura-Maria Krabbe , Okyaz Eminaga ...
来源:[J].BMC Cancer(IF 3.333), 2016, Vol.16 (1)Springer
摘要:... To facilitate decision-making we evaluated dynamic changes of alkaline phosphatase (ALP), lactate dehydrogenase (LDH) and prostate specific antigen (PSA) under therapy with Abiraterone.(#br) Methods(#br)Men with bone mCRPC (bmCRPC) on Abiraterone 12/2009-01/2014 were ana...
作者:R Nandha
来源:[J].Journal of Postgraduate Medicine(IF 1.263), 2012, Vol.58 (3), pp.203-206DOAJ
摘要:... Abiraterone acetate is an orally active, potent and selective inhibitor of 17 a hydroxylase and c 17, 20 lyase, which acts by decreasing the de novo production of androgens with no rise in steroids downstream. Multiple randomized trials have shown significant improvement of >...
作者:Neil M. Schultz , Scott C. Flanders , Samuel Wilson ...
来源:[J].Advances in Therapy(IF 2.125), 2018, Vol.35 (10), pp.1639-1655Springer
摘要:Abstract(#br) Introduction(#br)Enzalutamide and abiraterone acetate (plus prednisone) are new hormonal treatments for metastatic castration-resistant prostate cancer (mCRPC). This study compared treatment duration, healthcare resource utilization (HRU), and treatment costs for...
作者:Moritz Binder , Ben Y. Zhang , David W. Hillman ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2016, Vol.17 (7)DOAJ
摘要:Treatment with abiraterone acetate and prednisone (AA/P) prolongs survival in metastatic castration-resistant prostate cancer (mCRPC) patients. We evaluated the genetic variation in CYP17A1 as predictive of response to AA/P. A prospective collection of germline DNA prior to AA/P...

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