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作者:Salam Pradeep Singh , Bolin Kumar Konwar , Rajib Lochan Bezbaruah ...
来源:[J].Medicinal Chemistry Research(IF 1.612), 2013, Vol.22 (10), pp.4755-4765
摘要:... In this perspective, the aim of the present study is to focus on the molecular docking analysis of DHDPS enzyme against the analogues of 2-methylheptyl isonicotinate—a compound having strong antibacterial property against Mycobacterium tuberculosis . The analogues used ...
作者:Salam Pradeep Singh , T. C. Bora , R. L. Bezbaruah
来源:[J].Indian Journal of Microbiology(IF 0.457), 2012, Vol.52 (3), pp.427-432
摘要:Abstract(#br)Antibiotic resistance is a growing problem in multi-drug-resistant tuberculosis which is caused by Mycobacterium tuberculosis (MTB) . Hence there is an urgent need for designing or developing a novel or potent anti-tubercular agent. The Lysine/DAP biosynthetic pathwa...
作者:Salam Pradeep Singh , Rajib Lochan Bezbaruah , Tarun Chandra Bora
来源:[J].Journal of Biophysical Chemistry, 2012, Vol.3 (3), pp.233-237
摘要:Tuberculosis is thought to have infected one-third of the world’s population and antibiotic resistance is a growing problem in multi-drug-resistant tuberculosis which is caused by Mycobacterium tuberculosis (MTB). It has been reported that Mycobacterial cell walls are charac...
作者:Bordoloi Gojen N , Kumari Babita , Guha Arijit ...
来源:[J].Pest management science(IF 2.594), 2002, Vol.58 (3), pp.297-302
摘要:... The bioactive compound, with antifungal and antibacterial activity, was identified as 2-methylheptyl isonicotinate. The antifungal activity of live culture, culture broth and the isolated bioactive compound showed marked inhibition against dominant soil-borne phytopathogens s...
作者:Singh Salam Pradeep , Bora T C , Bezbaruah R L
来源:[J].Indian journal of microbiology(IF 0.457), 2012, Vol.52 (3), pp.427-32
摘要:Antibiotic resistance is a growing problem in multi-drug-resistant tuberculosis which is caused by Mycobacterium tuberculosis (MTB). Hence there is an urgent need for designing or developing a novel or potent anti-tubercular agent. The Lysine/DAP biosynthetic pathway is a promisi...
作者:Bogumiła Huras , Jerzy Zakrzewski , Maria Krawczyk ...
来源:[J].Medicinal Chemistry Research(IF 1.612), 2017, Vol.26 (3), pp.509-517
摘要:Abstract(#br)Homologs and analogs of 2-methylheptyl isonicotinate (new, natural antifungal and antibacterial antibiotic isolated from Streptomyces sp . 201): racemic 2-methylalkyl isonicotinates 4 and nicotinates 5 and enantiomerically enriched in the R and S isomers, 2-meth...
作者:Salam P. Singh , Chitta R. Deb , Sharif Uddin Ahmed ...
来源:[J].Current Enzyme Inhibition, 2016, Vol.12 (2), pp.123-133
摘要:... In this investigation, we performed pharmacophoreassisted virtual screening on analogs of 2-methyl heptyl isonicotinate against GlmU enzymeof Mycobacterium tuberculosis. Recent reports suggested the GlmU enzyme as a key protein in UDPGlcNAcbiosynthesis. Inhibition of the enzy...

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