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作者:Ezgi Ilhan , Timucin Ugurlu , Oya Kerimoglu
来源:[J].Open Journal of Chemistry, 2017, Vol.3 (1), pp.012-022同行科技出版社
摘要:Mini tablets are solid dosage forms with a diameter ≤ 3 mm and separated into subunits of conventional tablets. Production methods are similar to standard tablets, but the only difference is the use of multiple punches. They have advantageous for use in patients suffering fr...
作者:Rania M Hathout , AbdelKader A Metwally
来源:[J].Open Journal of Chemistry, 2018, Vol.4 (1), pp.001-002同行科技出版社
摘要:In one of the conversations between me and one of my senior colleagues, she told me “What lucky researchers you are!”, interested to know the reason behind this statement, I asked: “Why?!”, and she replied: “because in our time we didn’t have all these available se...
作者:Srinivas Maddi , Thirumaleswara Goud , Pratima Srivastava
来源:[J].Open Journal of Chemistry, 2017, Vol.3 (1), pp.001-011同行科技出版社
摘要:Drug-Drug interactions (DDI) is a serious clinical issue. An important mechanism underlying of DDI, is induction or inhibition of drug metabolizing enzymes (DMEs) and transporters that mediate metabolism, cellular uptake and effl ux of xenobiotics. DDI cannot be avoided in many c...
作者:Asma Noor , Muhammad Imran Qadir , Ardas Masood ...
来源:[J].Open Journal of Chemistry, 2017, Vol.3 (1), pp.023-025同行科技出版社
摘要:Mycobacterium Tuberculosis cause severe disease of lungs known as Tuberculosis. It is a major cause of morbidity and mortality even in the emerging countries also. However, to prepare an antibiotics drug against Mycobacterium tuberculosis is a major challenge. Two compounds Imiqu...
作者:Irena Kostova , Venceslava Atanasova , Magdalena Spasova Kondeva-Burdina ...
来源:[J].Open Journal of Chemistry, 2015, Vol.1 (1), pp.017-024同行科技出版社
摘要:The gallium(III) complex of orotic acid (HOA) was synthesized and its structure was determined by means of analytical and spectral analyses. Detailed vibrational analysis of HOA, sodium salt of HOA (NaOA) and Ga(III)-OA systems based on both the calculated and experimental s...
作者:R Kalirajan , S Jubie , B Gowramma
来源:[J].Open Journal of Chemistry, 2015, Vol.1 (1), pp.001-007同行科技出版社
摘要:Introduction: Chalcone, isoxazole and acridines have diverse biological activities. A series of novel chalcone and isoxazole substituted 9-anilinoacridines were synthesized for their antibacterial, larvicidal, activities.Methods: A series of novel chalcone and isoxazole subs...
作者:Noor ul Amin Mohsin , Muhammad Imran Qadir
来源:[J].Open Journal of Chemistry, 2015, Vol.1 (1), pp.008-012同行科技出版社
摘要:Structure activity relationship studies of 1,4-benzodiazepines have been discussed especially with their effects as antianxiety and anticonvulsants. The currently available benzodiazepines are associated with various side effects. Nowadays the purpose of these studies is to minim...
作者:Mardia Telep El-Sayed , Eman Kishk , El-Sayed Afsah
来源:[J].Open Journal of Chemistry, 2015, Vol.1 (1), pp.013-016同行科技出版社
摘要:The present work focused on exploring the reactivity of β-nitrostyrene towards Mannich reaction with different approaches. The synthesized nitro-Mannich bases were tested as antimicrobial agents that showed high activity against both gram positive and gram negative bacteria.
作者:Naman Krishna Kasera , Pramod Kumar Sharma , Rahul Gupta
来源:[J].Open Journal of Chemistry, 2015, Vol.1 (1), pp.025-029同行科技出版社
摘要:In recent years, robustness and surface engineering of dosage form made improvement in pharmacokinetics with decrease in dose of drug. Specifi city with adherence of ligands has now become the reality as surface modifi cation can easily deceive phagocytic system. Lipid molecules ...

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