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作者:Yonghong Zhang , Chen Li ...
来源:[J].PLOS ONE(IF 3.73), 2017, Vol.12 (7)PLOS
摘要:ELONGATED HYPOCOTYL 5 (HY5), a member of the bZIP gene family, is a positive regulator of the light signaling pathway in Arabidopsis thaliana . Whereas the hy5 mutant exhibits an elongated hypocotyl when grown in the light, the hy5 homolog ( hyh ) mutant does not. Although the fu...
作者:Yonghong Zhang , Shizue Mito
来源:[J].PLOS ONE(IF 3.73), 2017, Vol.12 (9)PLOS
摘要:Glioblastoma is the most common and lethal malignant primary brain tumor for which the development of efficacious chemotherapeutic agents remains an urgent need. The anti-helminthic drug niclosamide, which has long been in use to treat tapeworm infections, has recently attra...
作者:Yonghong Zhang , Zhengkun Tu ...
来源:[J].PLOS ONE(IF 3.73), 2017, Vol.12 (2)PLOS
摘要:Elucidating protective immunity against HCV is important for the development of a preventative vaccine. We hypothesize that spontaneous resolution of acute HCV infection offers clue to protective immune responses, and that DAA therapy affects the quality and quantity of HCV-speci...
作者:Yonghong Zhang , Keyi Xu ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (4)PLOS
摘要:The HIV pandemic remains the most serious challenge to public health worldwide. The hallmark characteristics of the disease is the eventual failure of the immune system to control opportunistic infections and death. However not everyone who has HIV develops the disease at the sam...
作者:Yonghong Zhang , Xiaojie Huang ...
来源:[J].PLOS ONE(IF 3.73), 2015, Vol.10 (3)PLOS
摘要:Over 95% of CD4 cell death occurs by Caspase-1-mediated pyroptosis during HIV infection. Caspase-3-mediated apoptosis accounts for the death in a small proportion of infected CD4 cells. To date, there have been no reports on the dynamics of Caspase-1 and Caspase-3 and their ...
作者:Yonghong Zhang , Xianqin Qiu ...
来源:[J].PLOS ONE(IF 3.73), 2016, Vol.11 (6)PLOS
摘要:The Hengduan Mountains are the core of the Sino-Himalayan Floristic Region. Rosa soulieana Crép. is an important wild rose species that is widely distributed in the Hengduan Mountains. To provide better future utilization of this wild rose, and also to add some possible proo...
作者:... Guiyan Wang , Weijun Tong , Yonghong Zhang
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (2)PLOS
摘要:This study aims to examine the association between inflammatory biomarkers and dyslipidemia and its components among Mongolians in China.;;Data were obtained from 2544 Mongolians via standard questionnaires and blood samples in Inner Mongolia, China. High sensitivity C-react...
作者:Yonghong Zhang , Jinfang Wang
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (1)PLOS
摘要:Glycerol metabolism has been well studied biochemically. However, the means by which glycerol functions in plant development is not well understood. This study aimed to investigate the mechanism underlying the effects of glycerol on root development in Arabidopsis thaliana ....
作者:Yonghong Zhang , Tongmin Mou ...
来源:[J].PLOS ONE(IF 3.73), 2012, Vol.7 (3)PLOS
摘要:Heading date and grain weight are two determining agronomic traits of crop yield. To date, molecular factors controlling both heading date and grain weight have not been identified. Here we report the isolation of a hemizygous mutation, heading and grain weight ( hgw ), which del...
作者:... Xiangqin Chao , Qiu Zhang , Yonghong Zhang
来源:[J].PLOS ONE(IF 3.73), 2013, Vol.8 (4)PLOS
摘要:Association between vitamin D insufficiency and hyperuricemia has not been reported so far. We aimed to study the association of vitamin D insufficiency with elevated serum uric acid among middle-aged and elderly Chinese Han women.;;We collected data from participants residi...

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