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作者:Qin Li , Zhen Cang ...
来源:[J].PLOS ONE(IF 3.73), 2017, Vol.12 (1)PLOS
摘要:Previous studies have revealed the association of lead (Pb) exposure with obesity. DNA methylation alteration has been suggested to be one of the regulatory mechanisms of obesity. We aimed to explore whether Pb exposure is related with weight gain and DNA methylation alteration.;...
作者:... Zhiyuan Hu , Zewen Wei , Qin Li
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (2)PLOS
摘要:Here, we provide direct evidence that using recombinant proteins expressed in eukaryotic cells as antigen is a practical way to generate monoclonal antibodies (mAbs) against heavily glycosylated proteins. Heavily glycosylated proteins are typically difficult targets for mAb gener...
作者:Qin Li , Sheila Vignali ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (3)PLOS
摘要:The causes of gastrointestinal complaints in irritable bowel syndrome (IBS) remain poorly understood. Altered nerve function has emerged as an important pathogenic factor as IBS mucosal biopsy supernatants consistently activate enteric and sensory neurons. We investigated th...
作者:Qin Li , Hui Li ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (6)PLOS
摘要:To examine the 20-year trends in the combined prevalence of overweight and obesity among children aged 0–6 years between 1995 and 2015 in Harbin, China, we selected altogether 49,553 children aged 0–6 years old by using a multistage stratified cluster sampling methods in Har...
作者:Qin Li , Han Yan ...
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (8)PLOS
摘要:Gemcitabine (GEM) is the standard first-line chemotherapy that provides limited clinical benefits for patients with locally advanced/metastatic pancreatic adenocarcinoma (LA/MPC). However, the fluorouracil derivatives (CAP and S-1) show promising efficacy in these patients. This ...
作者:... Shuang Chen , Zhen Yu , Qin Li
来源:[J].PLOS ONE(IF 3.73), 2016, Vol.11 (12)PLOS
摘要:Chongqing is the largest municipality and located in Southwestern of China, with over 30 million registered inhabitants. There are few reports regarding the epidemiology of influenza in Chongqing. The objective of the paper is to explore the epidemiology of influenza in Chon...
作者:Qin Li , Carl Beierkuhnlein ...
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (9)PLOS
摘要:It is inevitable that tree species will undergo considerable range shifts in response to anthropogenic induced climate change, even in the near future. Species Distribution Models (SDMs) are valuable tools in exploring general temporal trends and spatial patterns of potential ran...
作者:Qin Li , Li Qing ...
来源:[J].PLOS ONE(IF 3.73), 2015, Vol.10 (2)PLOS
摘要:The aims of this study were to investigate the effects of manganese (Mn) dust exposure on lung functions and evaluate the potential synergistic effect between smoking and Mn dust exposure among refinery workers.;;A retrospective study including 1658 workers in a ferromanganese re...
作者:Qin Li , Yi Chen ...
来源:[J].PLOS ONE(IF 3.73), 2016, Vol.11 (9)PLOS
摘要:The association ns between prediabetes and androgens have been rarely reported, especially in Chinese men. We aimed to investigate whether androgens were associated with the prevalence of prediabetes diagnosed with new American Diabetes Association criteria in Chinese men an...
作者:Qin Li , Pengfei Zhao ...
来源:[J].PLOS ONE(IF 3.73), 2015, Vol.10 (8)PLOS
摘要:The combination of chemotherapy and epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) currently has become the hotspot issue in the treatment of non-small lung cancer (NSCLC). This systematic review was conducted to compare the efficacy and safety of ...

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