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作者:... Daniel S. Johnson , Joshua S. Mincer , Sanford M. Simon
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (4)PLOS
摘要:We report a computational model for the assembly of HIV-1 Gag into immature viral particles at the plasma membrane. To reproduce experimental structural and kinetic properties of assembly, a process occurring on the order of minutes, a coarse-grained representation consisting of ...
作者:Thomas T. Joseph , Joshua S. Mincer
来源:[J].PLOS ONE(IF 3.73), 2016, Vol.11 (7)PLOS
摘要:General anesthetics bind reversibly to ion channels, modifying their global conformational distributions, but the underlying atomic mechanisms are not completely known. We examine this issue by way of the model protein Gloeobacter violaceous ligand-gated ion channel (GLIC) using ...

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