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作者:Georg Hempel
来源:[B].Elsevier Inc.2020Elsevier
摘要:Anticancer drugs are good candidates for therapeutic drug monitoring (TDM) because of their high toxicity and documented exposure–response relationship for many anticancer drugs. In contrast to this, a few years ago Peterson concluded that in oncology “…plasma concentra...
作者:Georg Hempel
来源:[B].Elsevier Inc.2004Elsevier
摘要:Publisher Summary This chapter introduces current concepts of dose finding in oncology and gives an update on applications of therapeutic drug monitoring in oncology. Anticancer drugs, especially those with cytostatic activity, are good candidates for therapeutic drug monitoring ...

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