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作者:Amanda Mocroft , Lene Ryom ...
来源:[J].PLOS Medicine(IF 16.269), 2017, Vol.14 (11)PLOS
摘要:The Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study has developed predictive risk scores for cardiovascular disease (CVD) and chronic kidney disease (CKD, defined as confirmed estimated glomerular filtration rate [eGFR] ≤ 60 ml/min/1.73 m2) event...
作者:Amanda Mocroft , Patricia Garcia De Olalla ...
来源:[J].PLOS ONE(IF 3.73), 2017, Vol.12 (4)PLOS
摘要:HIV controllers (HICs) spontaneously maintain HIV viral replication at low level without antiretroviral therapy (ART), a small number of whom will eventually lose this ability to control HIV viremia. The objective was to identify factors associated with loss of virological c...
作者:Amanda Mocroft , Jens D. Lundgren ...
来源:[J].PLOS Medicine(IF 16.269), 2015, Vol.12 (3)PLOS
摘要:Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding potentially nephrotox...
作者:... Robert Zangerle , Amanda Mocroft , Jan Van Lunzen
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (1)PLOS
摘要:The impact of immunosuppression despite virological suppression (immuno-virological discordance, ID) on the risk of developing fatal and non-fatal AIDS/non-AIDS events is unclear and remains to be elucidated.;;Patients in EuroSIDA starting at least 1 new antiretroviral drug ...
作者:... Ewa Firląg-Burkacka , Amanda Mocroft , Andrzej Horban
来源:[J].PLOS ONE(IF 3.73), 2016, Vol.11 (10)PLOS
摘要:The main objective of the TAK project is investigating barriers in accessing HIV care after HIV-diagnosis at the CBVCTs of central Poland. Here we describe factors associated with and changes over time in linkage to care and access to cART.;;Data collected in 2010–2013 in CB...
作者:Amanda Mocroft , Jacqueline Neuhaus ...
来源:[J].PLOS ONE(IF 3.73), 2012, Vol.7 (7)PLOS
摘要:Chronic kidney disease (CKD) is an important cause of morbidity and mortality in HIV-positive individuals. Hepatitis C (HCV) co-infection has been associated with increased risk of CKD, but prior studies lack information on potential mechanisms. We evaluated the association ...
作者:Amanda Mocroft , Jens D. Lundgren ...
来源:[J].PLOS Medicine(IF 15.253), 2013, Vol.10 (9)PLOS
摘要:Few studies have monitored late presentation (LP) of HIV infection over the European continent, including Eastern Europe. Study objectives were to explore the impact of LP on AIDS and mortality.;;LP was defined in Collaboration of Observational HIV Epidemiological Research E...
作者:Amanda Mocroft , Vincent Soriano ...
来源:[J].PLOS ONE(IF 3.73), 2013, Vol.8 (5)PLOS
摘要:Whereas it is well established that various soluble biomarkers can predict level of liver fibrosis, their ability to predict liver-related clinical outcomes is less clearly established, in particular among HIV/viral hepatitis co-infected persons. We investigated plasma hyalu...
作者:Amanda Mocroft , Stefan Esser ...
来源:[J].PLOS ONE(IF 3.73), 2013, Vol.8 (1)PLOS
摘要:Improved methods for targeting HIV testing among patients most likely to be infected are required; HIDES I aimed to define the methodology of a European wide study of HIV prevalence in individuals presenting with one of eight indicator conditions/diseases (ID); sexually tran...
作者:... Ole Kirk , Jens D. Lundgren , Amanda Mocroft
来源:[J].PLOS ONE(IF 3.73), 2012, Vol.7 (7)PLOS
摘要:Differences in access to care and treatment have been reported in Eastern Europe, a region with one of the fastest growing HIV epidemics, compared to the rest of Europe. This analysis aimed to establish whether there are regional differences in the mortality rate of HIV-posi...

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