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作者:Alfonso Iorio , Kathelijn Fischer ...
来源:[J].Thromb Haemost(IF 6.094), 2017, Vol.117 (6), pp.1023-1030
摘要:The prophylactic administration of factor IX (FIX) is considered the most effective treatment for haemophilia B. The inter-individual variability and complexity of the pharmacokinetics (PK) of FIX, and the rarity of the disease have hampered identification of an optimal treatment...
作者:... Matthew Cheah , Mark A. Crowther , Alfonso Iorio
来源:[J].Thromb Haemost(IF 6.094), 2017, Vol.117 (3), pp.589-594
摘要:Venous thromboembolism (VTE) is one of the most common complications in patients with brain tumours. There is limited data available in the literature on VTE treatment in these patients. We conducted a matched retrospective cohort study of patients with primary or metastatic...
作者:... Nancy Heddle , Alfonso Iorio , Mark Crowther
来源:[J].Thromb Haemost(IF 6.094), 2016, Vol.116 (5), pp.879-890
摘要:Urgent reversal of warfarin is required for patients who experience major bleeding or require urgent surgery. Treatment options include the combination of vitamin K and coagulation factor replacement with either prothrombin complex concentrate (PCC) or fresh frozen plasma (F...

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