European Cells and Materials (eCM)
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作者:S Gibbs , S Roffel , M Meyer ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.63-78European Cells and Materials (eCM)
摘要:Epithelium attachment to the tooth or abutment surface is necessary to form a biological seal preventing pathogens and irritants from penetrating the body and reaching the underlying soft tissues and bone, which in turn can lead to inflammation and subsequent bone resorption...
作者:M H Hagmeijer , L A Vonk , M Fenu ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.51-62European Cells and Materials (eCM)
摘要:Meniscus regeneration is an unmet clinical need as damage to the meniscus is common and causes early osteoarthritis. The aim of the present study was to investigate the feasibility of a one-stage cell-based treatment for meniscus regeneration by augmenting a resorbable collagen-b...
作者:G R Meloni , A Farran , B Mohanraj ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.23-34European Cells and Materials (eCM)
摘要:Articular cartilage is a specialised tissue that has a relatively homogenous endogenous cell population but a diverse extracellular matrix (ECM), with depth-dependent mechanical properties. Repair of this tissue remains an elusive clinical goal, with biological interventions...
作者:S Pitkänen , K Paakinaho , H Pihlman ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.35-50European Cells and Materials (eCM)
摘要:Most synthetic bone grafts are either hard and brittle ceramics or paste-like materials that differ in applicability from the gold standard autologous bone graft, which restricts their widespread use. Therefore, the aim of the study was to develop an elastic, highly porous a...
作者:V-T Duong , T-T Dang , J P Kim ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.1-13European Cells and Materials (eCM)
摘要:In the current study, a method is proposed to supply culture medium into a two-layered cell-laden tubular scaffold in order to enhance cell proliferation, confluence, and viability. The two-layered cell-laden tubular scaffold was made of calcium-alginate mixed with fibroblas...
作者:A Atasoy-Zeybek , A Ivkovic , T Beyzadeoglu ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.14-22European Cells and Materials (eCM)
摘要:Bone autografting remains the clinical model of choice for resolving problematic fractures. The precise mechanisms through which the autograft promotes bone healing are unknown. The present study examined the hypothesis that cells within the autograft secrete osteogenic fact...
作者:R P Trombetta , K L de Mesy Bentley , E M Schwarz ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.37, pp.431-443European Cells and Materials (eCM)
摘要:Implant-associated osteomyelitis is a chronic infection that complicates orthopaedic surgeries. Once infected, 50 % of patients suffer treatment failure, resulting in high healthcare costs. While various small animal models have been developed to investigate the efficacy of proph...
作者:F I Alagboso , M Budak , U Sommer ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.37, pp.444-466European Cells and Materials (eCM)
摘要:Despite the high incidence of metaphyseal bone fractures in patients, the mechanisms underlying the healing processes are poorly understood due to the lack of suitable experimental animal models. Hence, the present study was conducted to establish and characterise a clinically re...
作者:R M Wong , U Thormann , M H Choy ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.37, pp.420-430European Cells and Materials (eCM)
摘要:Most osteoporotic fractures occur at metaphyseal regions of long bones. The present study proposed a clinically relevant animal model that satisfied: i) induction of osteoporosis, ii) unilateral complete osteotomy at metaphysis, iii) internal fixation. 6 months old female Sprague...
作者:S Rumiński , I Kalaszczyńska , A Długosz ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.37, pp.382-401European Cells and Materials (eCM)
摘要:Expansion and differentiation of adipose-derived stem cells (ADSCs) in vitro are routinely performed in two-dimensional (2D) environments. The study hypothesis was that the utilisation of three-dimensional (3D) culture conditions, mimicking the natural stem cell niche, might incr...

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