European Cells and Materials (eCM)
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作者:E Delve , V Co , S C Regmi ...
来源:[J].Eur Cell Mater(IF 4.558), 2020, Vol.39, pp.48-64European Cells and Materials (eCM)
摘要:The roles of cell division control protein 42 homologue (CDC42) and actin polymerisation in regulating the phenotype of superficial-zone chondrocytes (SZCs) have been demonstrated in vitro; however, the signalling pathway(s) downstream have yet to be fully elucidated. The study h...
作者:M Fusellier , J Clouet , O Gauthier ...
来源:[J].Eur Cell Mater(IF 4.558), 2020, Vol.39, pp.18-47European Cells and Materials (eCM)
摘要:Appropriate cell sources, bioactive factors and biomaterials for generation of functional and integrated annulus fibrosus (AF) tissue analogues are still an unmet need. In the present study, the AF cell markers, collagen type I, cluster of differentiation 146 (CD146), mohawk...
作者:J Du , R G Long , T Nakai ...
来源:[J].Eur Cell Mater(IF 4.558), 2020, Vol.39, pp.1-17European Cells and Materials (eCM)
摘要:Appropriate cell sources, bioactive factors and biomaterials for generation of functional and integrated annulus fibrosus (AF) tissue analogues are still an unmet need. In the present study, the AF cell markers, collagen type I, cluster of differentiation 146 (CD146), mohawk...
作者:R Black , A J Grodzinsky
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.246-263European Cells and Materials (eCM)
摘要:While glucocorticoids have been used for over 50 years to treat rheumatoid and osteoarthritis pain, the prescription of glucocorticoids remains controversial because of potentially harmful side effects at the molecular, cellular and tissue levels. One member of the glucocort...
作者:O F Gardner , S C Juneja , H Whetstone ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.215-227European Cells and Materials (eCM)
摘要:In an effort to develop an effective source of clinically relevant cells and tissues for cartilage repair a directed differentiation method was used to generate articular chondrocytes and cartilage tissues from human embryonic stem cells (hESCs). It has previously been demonstrat...
作者:M W Laschke , M S Seifert , C Scheuer ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.188-200European Cells and Materials (eCM)
摘要:High glucose concentrations have been shown to activate endothelial cells and promote angiogenesis. In the present study, it was investigated whether high glucose concentrations could improve the vascularisation capacity of adipose-tissue-derived microvascular fragments (ad-...
作者:I Irastorza , J Luzuriaga , R Martinez-Conde ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.201-214European Cells and Materials (eCM)
摘要:Dental implants are the usual therapy of choice in the dental clinic to replace a loss of natural teeth. Over recent decades there has been an important progress in the design and manufacturing of titanium implant surfaces with the goal of improving their osteointegration. I...
作者:F E Freeman , D C Browe , J Nulty ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.168-187European Cells and Materials (eCM)
摘要:Interconnected porosity is critical to the design of regenerative scaffolds, as it permits cell migration, vascularisation and diffusion of nutrients and regulatory molecules inside the scaffold. 3D printing is a promising strategy to achieve this as it allows the control ov...
作者:F Shapiro , J Y Wu
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.137-167European Cells and Materials (eCM)
摘要:Cortical bone development is characterised by initial formation of woven bone followed by deposition of lamellar bone on the woven scaffold. This occurs in normal bone formation as an integral obligate self-assembly pattern throughout all vertebrate groups, with specific tem...
作者:A J Turlo , A J Mueller-Breckenridge , D E Zamboulis ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.123-136European Cells and Materials (eCM)
摘要:The main challenge in tendon injury management is suboptimal tissue healing that fails to re-establish original tendon function. Tissue bioengineering is a promising approach for tendon therapy, with potential to improve its functional outcomes. However, evaluation criteria for t...

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