European Cells and Materials (eCM)
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作者:R Black , A J Grodzinsky
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.246-263European Cells and Materials (eCM)
摘要:While glucocorticoids have been used for over 50 years to treat rheumatoid and osteoarthritis pain, the prescription of glucocorticoids remains controversial because of potentially harmful side effects at the molecular, cellular and tissue levels. One member of the glucocort...
作者:O F Gardner , S C Juneja , H Whetstone ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.215-227European Cells and Materials (eCM)
摘要:In an effort to develop an effective source of clinically relevant cells and tissues for cartilage repair a directed differentiation method was used to generate articular chondrocytes and cartilage tissues from human embryonic stem cells (hESCs). It has previously been demonstrat...
作者:M W Laschke , M S Seifert , C Scheuer ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.188-200European Cells and Materials (eCM)
摘要:High glucose concentrations have been shown to activate endothelial cells and promote angiogenesis. In the present study, it was investigated whether high glucose concentrations could improve the vascularisation capacity of adipose-tissue-derived microvascular fragments (ad-...
作者:I Irastorza , J Luzuriaga , R Martinez-Conde ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.201-214European Cells and Materials (eCM)
摘要:Dental implants are the usual therapy of choice in the dental clinic to replace a loss of natural teeth. Over recent decades there has been an important progress in the design and manufacturing of titanium implant surfaces with the goal of improving their osteointegration. I...
作者:F E Freeman , D C Browe , J Nulty ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.168-187European Cells and Materials (eCM)
摘要:Interconnected porosity is critical to the design of regenerative scaffolds, as it permits cell migration, vascularisation and diffusion of nutrients and regulatory molecules inside the scaffold. 3D printing is a promising strategy to achieve this as it allows the control ov...
作者:F Shapiro , J Y Wu
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.137-167European Cells and Materials (eCM)
摘要:Cortical bone development is characterised by initial formation of woven bone followed by deposition of lamellar bone on the woven scaffold. This occurs in normal bone formation as an integral obligate self-assembly pattern throughout all vertebrate groups, with specific tem...
作者:A J Turlo , A J Mueller-Breckenridge , D E Zamboulis ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.123-136European Cells and Materials (eCM)
摘要:The main challenge in tendon injury management is suboptimal tissue healing that fails to re-establish original tendon function. Tissue bioengineering is a promising approach for tendon therapy, with potential to improve its functional outcomes. However, evaluation criteria for t...
作者:C A Knuth , E Andres Sastre , N B Fahy ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.106-122European Cells and Materials (eCM)
摘要:n tissue engineering, endochondral ossification (EO) is often replicated by chondrogenically differentiating mesenchymal stromal cells (MSCs) in vitro and achieving bone formation through in vivo implantation. The resulting marrow-containing bone constructs are promising as a tre...
作者:T Ning , K Zhang , B Chin Heng ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.79-93European Cells and Materials (eCM)
摘要:Biological effects of pulsed electrical stimulation (PES) on cells and tissues have been intensively studied with the aim of advancing their biomedical applications. These effects vary significantly depending on PES parameters, cell and tissue types, which can be attributed to th...
作者:M Koolen , A Longoni , J van der Stok ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.94-105European Cells and Materials (eCM)
摘要:This study aimed at investigating in vitro and in vivo the efficiency of commercially available fibrin as a carrier for controlled and sustained bone morphogenetic protein-2 (BMP-2) release to induce bone formation and reduce the side effects of its use. In vitro release and...

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