F1000 Research Ltd
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作者:Karen Bride , David Teachey
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:Autoimmune lymphoproliferative syndrome (ALPS) is an inherited syndrome characterized by abnormal lymphocyte survival caused by failure of apoptotic mechanisms to maintain lymphocyte homeostasis. This failure leads to the clinical manifestations of non-infectious and non-malignan...
作者:Tina Lohse , Sabine Rohrmann , David Faeh ...
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:Body mass indices (BMIs) are applied to monitor weight status and associated health risks in populations. Binary or multinomial logistic regression models are commonly applied in this context, but are only applicable to BMI values categorized within a small set of defined ad hoc ...
作者:Jonathan P. Tennant , Jonathan M. Dugan , Daniel Graziotin ...
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:Peer review of research articles is a core part of our scholarly communication system. In spite of its importance, the status and purpose of peer review is often contested. What is its role in our modern digital research and communications infrastructure? Does it perform to the h...
作者:Ghassan Bandak , Kianoush B. Kashani
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:Over the past few years, chloride has joined the league of essential electrolytes for critically ill patients. Dyschloremia can occur secondary to various etiologic factors before and during patient admission in the intensive care unit. Some cases are disease-related; others, tre...
作者:Jiandong Zhao , Jiazhou Wang , Mingxia Cheng
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:Hepatocellular carcinoma (HCC) is a leading cause of cancer death in China and around the world. Tumoricidal doses of modern radiation therapy (RT) can now be safely delivered with excellent local control and minimal toxicity. Delivering adequate doses of radiation to the pr...
作者:Thomas Kesteman , Milijaona Randrianarivelojosia , Christophe Rogier
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:Background : Thanks to a considerable increase in funding, malaria control interventions (MCI) whose efficacy had been demonstrated by controlled trials have been largely scaled up during the last decade. Nevertheless, it was not systematically investigated whether this effi...
作者:Gideon Blecher , Khaled Almekaty , Odunayo Kalejaiye ...
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:In men undergoing radical treatment for prostate cancer, erectile function is one of the most important health-related quality-of-life outcomes influencing patient choice in treatment. Penile rehabilitation has emerged as a therapeutic measure to prevent erectile dysfunction...
作者:Felipe Batalini , Millena Gomes , Fábio I ...
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:Background: With the increase in prevalence of cancer in our society, we aim to clarify through primary data use what drives emergency department (ED) utilization among patients with cancer. Methods: This is a cross-sectional study. A direct survey was applied to cancer patients ...
作者:Prithviraj Bose , Varsha Gandhi
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:The last several years have witnessed a paradigm shift in the management of patients with chronic lymphocytic leukemia (CLL). The course of this very heterogeneous disease, traditionally treated with chemotherapeutic agents usually in combination with rituximab, typically has bee...
作者:Anna Skiada , Ioannis Pavleas , Maria Drogari-Apiranthitou
来源:[J].F1000Research, 2017, Vol.6F1000 Research Ltd
摘要:In the expanding population of immunocompromised patients and those treated in intensive care units, rare fungal infectious agents have emerged as important pathogens, causing invasive infections associated with high morbidity and mortality. These infections may present either as...

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