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作者:Cai He , Tao Zhou* , Li Liao
来源:[J].Advances in biology and medicine, 2019, Vol.4 (1)HCP
摘要:Abstract The aim of this study is to explore the relationship between miR-128 and interstitial cells of Cajal (ICCs) in the pathogenesis of constipation and the related mechanism. We observed that the expression of miR-128 and c-kit were significantly down-regulated in constipate...
作者:Lingli Zhu* , Zonghua Guan , Shiliang Zhang
来源:[J].Advances in biology and medicine, 2019, Vol.4 (1)HCP
摘要:Abstract Aim: The aim of this study is to explain the effects and mechanism of resveratrol to improve atherosclerosis in vivo study. Methods: SD rats were divided randomly into control group, vascular calcification model group and treatment group. Vascular calcification mode...
作者:Yu Zhou* , Yiping Wang , Zhengxu Deng
来源:[J].Advances in biology and medicine, 2019, Vol.4 (1)HCP
摘要:Abstract Non-small cell lung cancer (NSCLC) accounts for more than 80% of lung cancer and the high mortality probably be caused by early invasion and metastasis. LncRNA FOXD2-AS1 is involved in tumor proliferation, invasion and metastasis. Epithelial-to-mesenchymal transitio...
作者:Peidong Qing , Yun Cao* , Jianfeng Xu ...
来源:[J].Advances in biology and medicine, 2019, Vol.4 (1)HCP
摘要:Abstract Background Accumulating evidence indicated that microRNAs are involved in the pathogenesis of intervertebral disc degeneration (IDD). The roles of miR-183 in IDD have not been elucidated. Methods A total number of 60 patients with IDD were included in this study, and deg...
作者:Yunfei Gao , Xi Lu , Dongbo Luo ...
来源:[J].Advances in biology and medicine, 2019, Vol.4 (1)HCP
摘要:Abstract:Radiotherapy is the main treatment for many advanced esophageal squamous cell carcinoma (ESCC) patients. Recent studies demonstrated that patients with high level of long non-coding RNA (lncRNA) MALAT1 in tumor had poor prognosis. Thus, our study aims to investigate...
作者:Shilong Shu* , Faqiang Zhang , Ke Lan
来源:[J].Advances in biology and medicine, 2018, Vol.3 (4)HCP
摘要:Abstract: Gastric cancer (GC) remains one of the most common malignancy globally, with high incidence and mortality rates. The dysregulation of miR-768-3p has been observed in several types of tumors, and it is involved in the carcinogenesis of GC. This present study aimed to det...
作者:Xuqiang Wu* , Weijie Gu , Bing Zheng
来源:[J].Advances in biology and medicine, 2018, Vol.3 (4)HCP
摘要:Abstract Objective: This study aims to investigate the role and mechanism of miR-127 in rheumatoid arthritis (RA). Methods: Totally 30 cases of RA patients were enrolled and 30 cases of healthy volunteers were enrolled as the control group. Peripheral blood samples and synov...
作者:Yiwen Zhang* , Yan Xiong , Hongbo Pang
来源:[J].Advances in biology and medicine, 2018, Vol.3 (4)HCP
摘要:Abstract: Aim: To investigate the effects of quercetin on hypoxic-ischemic injury (HI) in neonatal mice and the mechanisms of action. Methods: 40 male C57BL/6J neonatal mice aging seven days were randomly divided into 4 groups: a sham with normal saline group (SOS), a sham w...
作者:Junling Wang* , Chunhua Zou , Fangfang Chen
来源:[J].Advances in biology and medicine, 2018, Vol.3 (4)HCP
摘要:Abstract: To provide reference for the prevention, diagnosis and treatment of diabetes by means of comprehensively analyzing the relationship between serum ferritin level and diabetes. The software of review manager 5 (Revman 5) was applied to analyze the data for meta analysis. ...
作者:Li Yang , Wancheng Li , Dan Yang ...
来源:[J].Advances in biology and medicine, 2018, Vol.3 (4)HCP
摘要:Abstract: Curcumin is a polyphenol compound with anti-inflammatory effect. It can reduce the oxidative stress response of asthmatic patients by inhibiting the production of NO, thus alleviating the occurrence of airway inflammation. In this study, we further studied the mole...

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