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作者:Rachmawati Ramadhana Mustofa , Iskandarsyah .
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.338-342IAS
摘要:Objective: This study aimed to prepare and characterize anti-acne ethosomes using the cold- and thin-layer hydration methods.Methods: A sonication step was included during ethosome preparation to improve the quality of the cold method. Azelaic acid, Phospholipon 90G,ethanol,...
作者:Effionora Anwar , Dyah Ayu Ratna Yulianti , Kurnia Sari Setio Putri
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.376-380IAS
摘要:Objective: This study aimed to determine the stability of microspheres of Sargassum plagyophyllum (brown seaweed) after preparation using spraydrying with maltodextrin DE 10–15 and during drying and storage.Methods: Aqueous extracts of brown seaweed were formulated into micr...
作者:Yahdiana Harahap , Ganesya Rita Putri , Herman Suryadi
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.331-334IAS
摘要:Objective: This study aimed to determine clopidogrel in plasma to obtain its pharmacokinetic profile using ultra-high-performance liquidchromatography-tandem mass spectrometry (UPLC-MS/MS).Methods: Clopidogrel analysis was performed in vivo by UPLC-MS/MS using validated meth...
作者:Rani Sauriasari , Yusna Fadliyyah Apriyanti , Dito Pramono
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.66-69IAS
摘要:Objective: The Ministry of Health (MoH) Regulation No. 30, 2014, about Health Service Standards defines the need for routine monitoring ofprescribing indicators for several diseases, including non-pneumonia acute respiratory tract infection (ARI).Methods: This study compares the ...
作者:Baitha Palanggatan Maggadani , Harmita . , Milza Lubnan
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.403-406IAS
摘要:Objective: This study aimed to validate an high-performance liquid chromatography method for analyzing undenatured Type II collagen preparationsusing a fluorescence detector.Methods: Based on the optimum analysis conditions, the compound was detected at an excitation wavelen...
作者:Yahdiana Harahap , Prastiwi Arum Sari , Catur Jatmika
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.126-129IAS
摘要:Objective: This study aimed to develop an analytical method for determining metformin concentrations in human dried blood spots (DBS) usingoptimal chromatographic conditions and DBS preparation methods and validate the analytical methods.Methods: Analysis metformin HCl perfo...
作者:Yahdiana Harahap , Nathania Leony , Letare Merry Chresia Silalahi ...
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.370-375IAS
摘要:Objective: This study was aimed to develop a highly sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) methodfor the simultaneous quantification of tamoxifen, endoxifen, and clomiphene (internal standard) levels in human plasma.Methods: Plasma ...
作者:Bashar Adi Wahyu Pandhita , Vivian Soetikno , Melva Louisa
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.152-154IAS
摘要:Objective: This study aimed to investigate the effect of nanocurcumin (NC) against cisplatin-induced acute kidney injury, focusing on Nrf2 and Keap1.Methods: Male Sprague-Dawley rats (n=23) were divided into five groups (Control, CP, CP+Cur, CP+50 NC, and CP+100 NC) and sacrifice...
作者:Arif Arrahman , Rezi Riadhi Syahdi , Hana Permatasari ...
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.168-171IAS
摘要:Objective: This study aimed to determine the inhibitory activity of 1-butyl-3-methylimidazolium bromide ([bmim]Br) extracts of melinjo seeds(Gnetum gnemon) on dipeptidyl peptidase-4 (DPP-4).Methods: Melinjo seeds were extracted by a [bmim]Br microwave-assisted method using variou...
作者:Yahdiana Harahap , Anisa Maulidina , Delly Ramadon
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.392-395IAS
摘要:Objective: The aim of this study was to optimize and validate a plasma clopidogrel analysis method using liquid chromatography tandem-massspectrometry.Methods: Plasma samples were analyzed using a BEH C18 column (1.7 μm; 100 mm×2.1 mm), the mobile phase was 0.1% formic acid ...

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