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作者:Guang Xu , David H. Walker , Daniel Jupiter ...
来源:[J].PLOS Neglected Tropical Diseases(IF 4.569), 2017, Vol.11 (11)PLOS
摘要:Scrub typhus is a serious public health problem in the Asia-Pacific area. It threatens one billion people globally, and causes illness in one million people each year. Caused by Orientia tsutsugamushi , scrub typhus can result in severe multiorgan failure with a case fatality rat...
作者:Bryony N. Parsons , Umer Z. Ijaz , Rosalinda D’Amore ...
来源:[J].PLOS Pathogens(IF 9.127), 2017, Vol.13 (11)PLOS
摘要:Several conditions associated with reduced gastric acid secretion confer an altered risk of developing a gastric malignancy. Helicobacter pylori- induced atrophic gastritis predisposes to gastric adenocarcinoma, autoimmune atrophic gastritis is a precursor of type I gastric neuro...
作者:Sanandan Malhotra , Shelby Winans , Gary Lam ...
来源:[J].PLOS Pathogens(IF 9.127), 2017, Vol.13 (11)PLOS
摘要:Avian leukosis virus (ALV) is a simple retrovirus that causes a wide range of tumors in chickens, the most common of which are B-cell lymphomas. The viral genome integrates into the host genome and uses its strong promoter and enhancer sequences to alter the expression of nearby ...
作者:Minseung Choi , Diane P. Genereux , Jamie Goodson ...
来源:[J].PLOS Genetics(IF 8.694), 2017, Vol.13 (11)PLOS
摘要:In storing and transmitting epigenetic information, organisms must balance the need to maintain information about past conditions with the capacity to respond to information in their current and future environments. Some of this information is encoded by DNA methylation, which ca...
作者:Tereza Magalhaes , Cynthia Braga , Marli T. Cordeiro ...
来源:[J].PLOS Neglected Tropical Diseases(IF 4.569), 2017, Vol.11 (11)PLOS
摘要:Several arboviruses, including dengue virus (DENV), Zika virus (ZIKV) and chikungunya virus (CHIKV), transmitted by Aedes mosquitoes, circulate in northeast Brazil. Diseases caused by these viruses are of great public health relevance, however, their epidemiological features...
作者:Xiangbin Teng , Xing Tian , Jess Rowland ...
来源:[J].PLOS Biology(IF 11.452), 2017, Vol.15 (11)PLOS
摘要:Natural sounds convey perceptually relevant information over multiple timescales, and the necessary extraction of multi-timescale information requires the auditory system to work over distinct ranges. The simplest hypothesis suggests that temporal modulations are encoded in ...
作者:Nur Syafiqah Mohamad Ishak , Quang Dang Nong , Tomoaki Matsuura ...
来源:[J].PLOS Genetics(IF 8.694), 2017, Vol.13 (11)PLOS
摘要:Divergence of upstream regulatory pathways of the transcription factor Doublesex ( Dsx ) serves as a basis for evolution of sex-determining mechanisms in animals. However, little is known about the regulation of Dsx in environmental sex determination. In the crustacean Daphn...
作者:Mark A. Boyd , Amanda Mocroft , Lene Ryom ...
来源:[J].PLOS Medicine(IF 16.269), 2017, Vol.14 (11)PLOS
摘要:The Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study has developed predictive risk scores for cardiovascular disease (CVD) and chronic kidney disease (CKD, defined as confirmed estimated glomerular filtration rate [eGFR] ≤ 60 ml/min/1.73 m2) event...

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