Future Science Group期刊
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Is ethics failing to keep up with scientific advances?
作者：Francesca Lake
来源：[J].BioTechniques(IF 2.399), 2019, pp.-Future Science Group
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    Different epigenetic clocks reflect distinct pathophysiological features of multiple sclerosis
    作者：Eleftheria Theodoropoulou , Lars Alfredsson , Fredrik Piehl ...
    来源：[J].Epigenomics(IF 2.433), 2019, pp.-Future Science Group
    摘要：Aim: Accumulating evidence links epigenetic age to diseases and age-related conditions, but little is known about its association with multiple sclerosis (MS). Materials & methods: We estimated epigenetic age acceleration measures using DNA methylation from blood or sorted cells ...
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      The public perception of the facilitators and barriers to implementing personalized medicine: a systematic review
      作者：Ciara Holden , Lauren Bignell , Somnath Mukhopadhyay ...
      来源：[J].Per. Med.(IF 1.51), 2019, pp.-Future Science Group
      摘要：The integration of personalized medicine (PM) into mainstream healthcare will only be successful if the public understands and supports this change. The aim was to understand the public perception of the barriers and facilitators towards the use of PM. A systematic review of the ...
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        ELIMU-MDx: a web-based, open-source platform for storage, management and analysis of diagnostic qPCR data
        作者：Silvan Krähenbühl , Fabian Studer , Etienne Guirou ...
        来源：[J].BioTechniques(IF 2.399), 2019, pp.-Future Science Group
        摘要：The Electronic Laboratory Information and Management Utensil for Molecular Diagnostics (ELIMU-MDx) is a user-friendly platform designed and built to accelerate the turnaround time of diagnostic qPCR assays. ELIMU-MDx is compliant with Minimum Information for Publication of Quanti...
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          Preparation and characterization of human size whole heart for organ engineering: scaffold microangiographic imaging
          作者：Aram Akbarzadeh , Reza Khorramirouz , Fariba Ghorbani ...
          来源：[J].Regen. Med.(IF 3.873), 2019, pp.-Future Science Group
          摘要：Definitive treatment for end-stage heart failure is heart transplantation, however, this is associated with several limitations. Aim: We decellularized and assessed ovine hearts through coronary perfusion. To evaluate in situ recellularization, a decellular graft was transpl...
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            Antithrombotic therapy in acute coronary syndrome and stable coronary artery disease patients with atrial fibrillation: a 3-year retrospective cohort study
            作者：Jun Wu , Shenglan Lin , Chen Men ...
            来源：[J].Per. Med.(IF 1.51), 2019, pp.-Future Science Group
            摘要：Aim: Acute coronary syndrome (ACS) and stable coronary artery disease (SCAD) occur frequently in patients with atrial fibrillation (AF). However, the optimal antithrombotic therapy is still debated. Methods & results: We analyzed 976 coronary artery disease patients with AF ...
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              Efficacy and safety of direct-acting antivirals for treatment-naive patients with genotype 1 hepatitis C virus infection
              作者：Xiaobo Zhu , Mingqi Wang , Mei Liu ...
              来源：[J].Per. Med.(IF 1.51), 2019, pp.-Future Science Group
              摘要：This systematic review was performed on the basis of Preferred Reporting Items for Systematic Reviews and Meta-analyses and Cochrane recommendations to compare sustained virological response (SVR12) and the serious adverse events in patients treated by directing-acting antivirals...
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                Impact of CYP3A4/5 and ABCB1 polymorphisms on tacrolimus exposure and response in pediatric primary nephrotic syndrome
                作者：Lingfei Huang , Junyan Wang , Jufei Yang ...
                来源：[J].Pharmacogenomics(IF 3.857), 2019, Vol.20 (15), pp.1071-1083Future Science Group
                摘要：Aim: To evaluate the impact of CYP3A4*1G , CYP3A5*3 and ABCB1-C3435T polymorphisms on tacrolimus concentrations, efficacy and tolerance in pediatric primary nephrotic syndrome. Methods: Dose-adjusted concentrations (C0/D), daily dose, frequency and time to relapse, cum...
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                  Twelve-month healthcare utilization and expenditures in Medicare fee-for-service patients with clinically significant mitral regurgitation
                  作者：Hirsch S Mehta , Joanna Van Houten , Patrick Verta ...
                  来源：[J].J. Comp. Eff. Res., 2019, Vol.8 (13), pp.1089-1097Future Science Group
                  摘要：Aim: This study sought to quantify the healthcare burden of Medicare patients with clinically significant mitral regurgitation (sMR). Materials & methods: Proxy definitions were used for sMR, including MR surgery, atrial fibrillation, pulmonary hypertension or >2 echocardiograms....
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                    A stepwise approach to implementing pharmacogenetic testing in the primary care setting
                    作者：Kristin Wiisanen Weitzel , Benjamin Q Duong , Meghan J Arwood ...
                    来源：[J].Pharmacogenomics(IF 3.857), 2019, Vol.20 (15), pp.1103-1112Future Science Group
                    摘要：Pharmacogenetic testing can help identify primary care patients at increased risk for medication toxicity, poor response or treatment failure and inform drug therapy. While testing availability is increasing, providers are unprepared to routinely use pharmacogenetic testing ...
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